Is interleukin-18 associated with polycystic ovary syndrome?
نویسندگان
چکیده
منابع مشابه
Is interleukin-18 associated with polycystic ovary syndrome?
BACKGROUND Recent research show that polycystic ovary syndrome (PCOS) may have an association with low-grade chronic inflammation, IL-18 is considered as a strong risk marker of inflammation. METHODS To investigate serum IL-18 concentrations in PCOS patients and focus on its relationship between obesity and insulin resistance (IR). Sixty consecutive women with PCOS and thirty controls were re...
متن کاملInvestigation of genetic factors associated with polycystic ovary syndrome
Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders and causes 75% of infertility due to ovulation disorders in reproductive age. Women with PCOS have oligomenorrhea and hyperandrogenism that affect their quality of life and fertility at the same time. This syndrome has been one of the most controversial endocrine issues for many years. Research today su...
متن کاملPolycystic ovary syndrome is associated with endothelial dysfunction.
BACKGROUND We recently reported endothelial dysfunction as a novel cardiovascular risk factor associated with insulin resistance/obesity. Here, we tested whether hyperandrogenic insulin-resistant women with polycystic ovary syndrome (PCOS) who are at increased risk of macrovascular disease display impaired endothelium-dependent vasodilation and whether endothelial function in PCOS is associated...
متن کاملAssociation of polymorphisms of interleukin-18 gene promoter region with polycystic ovary syndrome in chinese population
BACKGROUND Recent research shows that polycystic ovary syndrome (PCOS) may have an association with low-grade chronic inflammation, and that PCOS may induce an increase in serum interleukin-18 (IL-18) levels. METHODS To investigate the polymorphisms of the IL-18 gene promoters with PCOS, two single nucleotide polymorphisms (SNPs) in the promoter of the IL-18 gene (at positions -607C/A and -13...
متن کاملPolycystic ovary syndrome. Polycystic ovary syndrome.
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2011
ISSN: 1477-7827
DOI: 10.1186/1477-7827-9-7